Genetically Transmitted Disease : Marfan Syndrome

So, the genetically transmitted disease that I found has the name of Marfan Syndrome. It is a genetic disorder in the connective part tissues. There is a change on one of the pair in Chromosome number 15, which creates Fibrillin. Our body is connected by tissues and it is made of a protein. Fibrilin genes makes a protein name Fibrillin-1. The disorder happen when it improves or create more of the fibrillin-1 to TBF-Beta.Then, there will be problems everywhere such as heart, blood vessels, bones, joints, eyes and lungs. It has the total affect on the human body, but also the human mind for they are stress of being objected in society. People who has Marfan Syndrome usually has a trait of long arms and legs,scoliosis, flat feet and has chest that sinks in or humps out. The condition of this syndrome to be pass down is by a Autosomal Dominant pattern. This syndrome also usual happen to those family who never has the history of having these syndrome. From the data I searched,both male and female can be affected and be carriers. Abraham Lincoln is one of the famous people who experienced the Marfan Syndrome. Other famous people that had this syndrome was the famous pianist, Sergei Rachmaninov , as well as the famous sportsman, Michael Phelps. Even having this disease, these people still are recognized around the world and achieved so many things.